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  • Modeling Liver Toxicity

    Using mechanistic modeling to solve liver toxicity problems

    DILIsym Services, Inc. utilizes the DILIsym® software to evaluate the Drug Induced Liver Injury (DILI) and hepatotoxic risk for compounds throughout the clinical development pipeline.

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    “We look forward to future efforts to apply this model (DILIsym®) for prediction of hepatotoxicity that has not been clinically observed.” - Shon and Abernethy, 2014 Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, FDA

  • Predicting DILI

    Designed to be used during drug development, the DILIsym® modeling software provides an enhanced understanding of DILI hazards at various stages of development.

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  • DILI Biomarker Analysis

    DILIsym® has been used to quantify liver injury based on measured biomarkers to support interactions with regulatory agencies.

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  • Support Clinical Development Decisions

    Predictions made with DILIsym® are placed within the context of decisions facing pharma during clinical development.

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DILIsym Services, Inc. retains an association with the DILI-sim Initiative. More information can be found at

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